A man is in hospital following a stabbing Melbourne yesterday.

Police and emergency services were called to Melton South just after 3:40PM on Thursday. 

Investigators were told the victim was stabbed by a man around Rowell Court, before fleeing to a Bottlemart store on Exford Road.

The 47-year-old victim was taken to the Royal Melbourne Hospital in a serious condition with upper body injuries.

The pair are thought to know each other.