A coach driver has died after his bus carrying 60 passengers crashed into the dislodged trailers of a B-double truck on the Western Highway in Victoria.

Police believe the trailers of the truck, which was travelling in front of the bus, dislodged and blocked the highway in both directions, causing the crash and trapping the driver, who died.

At least eight people have been injured with two of those in a serious condition, police said.

The accident happened near Pimpinio about 2am on Thursday.

The highway is closed in both directions as a result of the crash, with diversions in place and detectives at the scene.

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With AAP. 

 

KIIS 1011 Melbourne